• Non Hodgkin Lymphoma
• Io9

FDA Box Warning. Severe and sometimes fatal hepatitis has occurred, even after many months of treatment. Risk increases with age until 64, then decreases after age 65.

Risk also rises with daily alcohol consumption. Monitor patients carefully and interview them monthly. For persons aged 35 and older, also measure liver enzymes before therapy starts and periodically throughout. Isoniazidassociated hepatitis usually arises during first 3 months of therapy. Hepatitis risk also increases with daily alcohol use, chronic hepatic disease, and injection drug use.

Definition from Wiktionary, the free dictionary. 2.1 a; 2.2 b; 2.3 c; 2.4 d; 2.5 e; 2.6 f; 2.7 g; 2.8 h; 2.9 i; 2.10 j; 2.11 k; 2.12 l; 2.13 m; 2.14 n. In other languages. Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections do not have symptoms, in which case it is known as latent tuberculosis.

Recent report suggests increased risk of fatal hepatitis among women; risk also may increase during postpartum period. If adverse effects or signs and symptoms of hepatic damage occur, discontinue drug promptly. Tuberculosis patients with Isoniazidassociated hepatitis should receive appropriate treatment with alternative drugs. If isoniazid must be restarted, do so only after symptoms and laboratory abnormalities resolve. Restart in small and gradually increasing doses, and withdraw drug immediately at any indication of recurrent liver involvement.

Defer preventive treatment in patients with acute hepatic disease. Indications and dosages➣ Active tuberculosis (TB)Adults: 5 mg/kg P.O. (maximum of 300 mg/day) daily as a single dose, or 15 mg/kg (maximum of 900 mg/day) two to three times weekly; given with other agentsChildren: 10 to 15 mg/kg P.O. (maximum of 300 mg/day) daily as a single dose, or 20 to 40 mg/kg (maximum of 900 mg/day) two to three times weekly➣ To prevent TB in patients exposed to active diseaseAdults: 300 mg P.O.

Daily as a single dose for 6 to 12 monthsChildren and infants: 10 mg/kg P.O. Daily as a single dose for up to 12 months. Adverse reactionsCNS: peripheral neuropathy, dizziness, memory impairment, slurred speech, psychosis, toxic encephalopathy, seizuresEENT: visual disturbancesGI: nausea, vomitingGU: gynecomastiaHematologic: eosinophilia, methemoglobinemia, hemolytic anemia, aplastic anemia, agranulocytosis, thrombocytopeniaHepatic: hepatitisMetabolic: pyridoxine deficiency, hyperglycemia, metabolic acidosisRespiratory: dyspneaOther: fever, pellagra, lupuslike syndrome, injection site irritation, hypersensitivity reaction. Patient teaching.

Advise patient to take once daily on empty stomach, 1 hour before or 2 hours after meals.

Toronto Star. 26 November 2013. Retrieved 26 November 2013. The Globe and Mail. 27 November 2013. Retrieved 26 November 2013.

Non Hodgkin Lymphoma

The Globe and Mail. 26 November 2013. Retrieved 26 November 2013. ^ Cousineau, Sophie (2013-11-28). Retrieved 2013-12-20. Retrieved 22 December 2013. Retrieved 29 January 2014.

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Io9

Retrieved 29 January 2014., CTV News, June 9, 2008.External links. (in French). (in English)Preceded byNHL French network broadcast partnerin Canada-Succeeded.